Getting it right: 3D cell cultures for the assessment of photosensitizers for photodynamic therapy

Future Med Chem. 2015;7(15):1957-60. doi: 10.4155/fmc.15.133. Epub 2015 Oct 23.

Authors

Mathias O Senge¹, Shelley Stafford²

Affiliations

¹ Medicinal Chemistry, Institute of Molecular Medicine, Trinity Centre for Health Sciences, Trinity College Dublin, St James's Hospital, Dublin 8, Ireland.
² School of Chemistry, SFI Tetrapyrrole Laboratory, Trinity Biomedical Sciences Institute, 152-160 Pearse Street, Trinity College Dublin, The University of Dublin, Dublin 2, Ireland.

PMID: 26496381
DOI: 10.4155/fmc.15.133

No abstract available

Keywords: 3D cell cultures; drug development; in vitro models; photodynamic therapy; photomedicine; photosensitizers.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Agents / chemistry
Antineoplastic Agents / pharmacology*
Cell Culture Techniques*
Humans
Neoplasms / drug therapy*
Neoplasms / pathology
Photochemotherapy*
Photosensitizing Agents / chemistry
Photosensitizing Agents / pharmacology*

Substances

Antineoplastic Agents
Photosensitizing Agents