Analysis of factors in successful nasal endoscopic resection of nasopharyngeal angiofibroma

Acta Otolaryngol. 2016;136(2):205-13. doi: 10.3109/00016489.2015.1099734. Epub 2015 Oct 23.

Abstract

Conclusions: Endoscopic resection of nasopharyngeal angiofibroma is less traumatic, causes less bleeding, and provides a good curative effect. Using pre-operative embolization and controlled hypotension, reasonable surgical strategies and techniques lead to successful resection tumors of a maximum Andrews-Fisch classification stage of III.

Objective: To investigate surgical indications, methods, surgical technique, and curative effects of transnasal endoscopic resection of nasopharyngeal angiofibroma, this study evaluated factors that improve diagnosis and treatment, prevent large intra-operative blood loss and residual tumor, and increase the cure rate.

Methods: A retrospective analysis was performed of the clinical data and treatment programs of 23 patients with nasopharyngeal angiofibroma who underwent endoscopic resection with pre-operative embolization and controlled hypotension. The surgical method applied was based on the size of tumor and extent of invasion. Curative effects were observed.

Results: No intra-operative or perioperative complications were observed in 22 patients. Upon removal of nasal packing material 3-7 days post-operatively, one patient experienced heavy bleeding of the nasopharyngeal wound, which was treated compression hemostasis using post-nasal packing. Twenty-three patients were followed up for 6-60 months. Twenty-two patients experienced cure; one patient experienced recurrence 10 months post-operatively, and repeat nasal endoscopic surgery was performed and resulted in cure.

Keywords: Nasal endoscopy; prognosis; surgery; treatment.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Angiofibroma / pathology
  • Angiofibroma / surgery*
  • Blood Loss, Surgical / prevention & control*
  • Child
  • Endoscopy / methods*
  • Female
  • Humans
  • Male
  • Nasal Surgical Procedures / methods*
  • Nasopharyngeal Neoplasms / pathology
  • Nasopharyngeal Neoplasms / surgery*
  • Neoplasm Staging
  • Retrospective Studies
  • Treatment Outcome
  • Young Adult