Abstract
An efficient and simple synthesis of novel and densely substituted N-benzyl-1H-pyrroles 6a-r is described by a 1,4-addition/isomerization/ring closure/demetalation cascade process of alkynyl Fischer carbene complexes 1a-f and 2a and α-imino glycine methyl esters 3a, b, d, g, h, and k promoted with LDA.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Glycine / analogs & derivatives*
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Glycine / chemistry
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Imines / chemistry*
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Methane / analogs & derivatives*
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Methane / chemistry
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Molecular Structure
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Pyrroles / chemical synthesis*
Substances
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Imines
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Pyrroles
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carbene
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glycine methyl ester
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Methane
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Glycine