1 St. George's Healthcare NHS Trust and St. George's University of London, Tooting, London, United Kingdom, m.cecconi@nhs.net St. George's Healthcare NHS Trust and St. George's University of London, Tooting, London, United Kingdom Servicio de Cuidados Intensivos y Urgencias, Hospital SAS de Jerez, Jerez de la Frontera, Spain Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania St. George's Healthcare NHS Trust and St. George's University of London, Tooting, London, United Kingdom.