First report of New Delhi metallo-β-lactamase 5 (NDM-5)-producing Escherichia coli from blood cultures of three leukemia patients

Li-Ping Zhang; Wen-Cheng Xue; Dong-Ya Meng

doi:10.1016/j.ijid.2015.10.006

First report of New Delhi metallo-β-lactamase 5 (NDM-5)-producing Escherichia coli from blood cultures of three leukemia patients

Int J Infect Dis. 2016 Jan:42:45-46. doi: 10.1016/j.ijid.2015.10.006. Epub 2015 Oct 23.

Authors

Li-Ping Zhang¹, Wen-Cheng Xue², Dong-Ya Meng³

Affiliations

¹ Postgraduate Training Base of General Hospital of Shenyang Military Command, Liaoning Medical University, Jinzhou, China.
² Clinical Laboratory, General Hospital of Shenyang Military Command, Shenyang, China.
³ Clinical Laboratory, General Hospital of Shenyang Military Command, Shenyang, China. Electronic address: 13309889399@189.cn.

PMID: 26482388
DOI: 10.1016/j.ijid.2015.10.006

Abstract

We report the first occurrence of New Delhi metallo-β-lactamase 5 (NDM-5) in carbapenem-resistant Escherichia coli isolated from blood cultures of three leukemia patients in northern China. These patients had at some time been hospitalized in the hematology department of the same hospital. All isolates were ST167 with identical pulsed-field gel electrophoresis patterns, suggesting a likely hospital transmission.

Keywords: Carbapenem-resistant; Escherichia coli; Multilocus sequence typing (MLST); New Delhi metallo-β-lactamase 5 (NDM-5); Pulsed-field gel electrophoresis (PFGE).

MeSH terms

Adult
Bacteremia / microbiology*
Carbapenems / pharmacology
China
Electrophoresis, Gel, Pulsed-Field
Escherichia coli / drug effects
Escherichia coli / enzymology*
Humans
Leukemia / microbiology*
Male
Middle Aged
beta-Lactamases / biosynthesis*

Substances

Carbapenems
beta-Lactamases