Abatacept alleviates severe autoimmune symptoms in a patient carrying a de novo variant in CTLA-4

Affiliations

• ¹ Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea.
• ² Department of Pediatrics, Seoul National University Hospital, Seoul, Korea.
• ³ School of Life Sciences and Integrative Aging Research Center, Gwangju Institute of Science and Technology, Gwangju, Korea.
• ⁴ Department of Pathology, Seoul National University Hospital, Seoul, Korea.
• ⁵ Department of Pediatrics, Seoul National University Hospital, Seoul, Korea; Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.
• ⁶ Department of Pediatrics, Seoul National University Hospital, Seoul, Korea. Electronic address: kojs@snu.ac.kr.
• ⁷ School of Life Sciences and Integrative Aging Research Center, Gwangju Institute of Science and Technology, Gwangju, Korea. Electronic address: sgpark@gist.ac.kr.
• ⁸ Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea; Department of Pediatrics, Seoul National University Hospital, Seoul, Korea. Electronic address: murimchoi@snu.ac.kr.