Characteristics of the Exposure-Response Relationship of Particulate Matter and Mortality: A Time Series Analysis of 7 Cities in China

J Occup Environ Med. 2015 Oct;57(10):e93-100. doi: 10.1097/JOM.0000000000000541.

Abstract

Objectives: To explore the characteristics of the exposure-response relationship of particulate matter concentration and mortality on the multicity scale in China.

Methods: Generalized additive models were used to explore the short-term effects of particulate matter with an aerodynamic diameter of less than 10 μm (PM10) on mortality while adjusting for confounding variables, including seasonal periodicity, air temperature, relative humidity, day-of-the-week effect, and holiday effect. Additionally, possible PM10 thresholds for daily mortality were evaluated.

Results: In most cities, the relationships of PM10 concentration and daily cause-specific mortalities were all nearly linear when PM10 concentration was below 150 μg/m3. The estimated PM10 thresholds associated with nonaccidental and cardiovascular mortalities were 80 μg/m3 and 45 μg/m3, respectively.

Conclusions: Our findings indicated that, at least in China, the PM10 pollutant has threshold effects.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Air Pollutants / analysis
  • Air Pollutants / toxicity*
  • Air Pollution / adverse effects*
  • Air Pollution / analysis
  • Air Pollution / statistics & numerical data
  • Cardiovascular Diseases / mortality
  • China / epidemiology
  • Cities
  • Environmental Exposure / adverse effects*
  • Environmental Exposure / analysis
  • Environmental Exposure / statistics & numerical data
  • Humans
  • Models, Statistical
  • Mortality*
  • Particulate Matter / analysis
  • Particulate Matter / toxicity*
  • Poisson Distribution
  • Urban Health / statistics & numerical data*

Substances

  • Air Pollutants
  • Particulate Matter