Faster extubation time with more stable hemodynamics during extubation and shorter total surgical suite time after propofol-based total intravenous anesthesia compared with desflurane anesthesia in lengthy lumbar spine surgery

Chueng-He Lu; Zhi-Fu Wu; Bo-Feng Lin; Meei-Shyuan Lee; Chin Lin; Yuan-Shiou Huang; Yi-Hsuan Huang

doi:10.3171/2015.4.SPINE141143

Faster extubation time with more stable hemodynamics during extubation and shorter total surgical suite time after propofol-based total intravenous anesthesia compared with desflurane anesthesia in lengthy lumbar spine surgery

J Neurosurg Spine. 2016 Feb;24(2):268-274. doi: 10.3171/2015.4.SPINE141143. Epub 2015 Oct 13.

Authors

Chueng-He Lu¹, Zhi-Fu Wu¹, Bo-Feng Lin¹, Meei-Shyuan Lee², Chin Lin³, Yuan-Shiou Huang¹, Yi-Hsuan Huang¹

Affiliations

¹ Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center; and.
² School of Public Health and.
³ Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan, Republic of China.

PMID: 26460755
DOI: 10.3171/2015.4.SPINE141143

Abstract

OBJECT Anesthesia techniques can contribute to the reduction of anesthesia-controlled time and may therefore improve operating room efficiency. However, little is known about the difference in anesthesia-controlled time between propofol-based total intravenous anesthesia (TIVA) and desflurane (DES) anesthesia techniques for prolonged lumbar spine surgery under general anesthesia. METHODS A retrospective analysis was conducted using hospital databases to compare the anesthesia-controlled time of lengthy (surgical time > 180 minutes) lumbar spine surgery in patients receiving either TIVA via target-controlled infusion (TCI) with propofol/fentanyl or DES/fentanyl-based anesthesia, between January 2009 and December 2011. A variety of time intervals (surgical time, anesthesia time, extubation time, time in the operating room, postanesthesia care unit [PACU] length of stay, and total surgical suite time) comprising perioperative hemodynamic variables were compared between the 2 anesthesia techniques. RESULTS Data from 581 patients were included in the analysis; 307 patients received TIVA and 274 received DES anesthesia. The extubation time was faster (12.4 ± 5.3 vs 7.0 ± 4.5 minutes, p < 0.001), and the time in operating room and total surgical suite time was shorter in the TIVA group than in the DES group (326.5 ± 57.2 vs 338.4 ± 69.4 minutes, p = 0.025; and 402.6 ± 60.2 vs 414.4 ± 71.7 minutes, p = 0.033, respectively). However, there was no statistically significant difference in PACU length of stay between the groups. Heart rate and mean arterial blood pressure were more stable during extubation in the TIVA group than in the DES group. CONCLUSIONS Utilization of TIVA reduced the mean time to extubation and total surgical suite time by 5.4 minutes and 11.8 minutes, respectively, and produced more stable hemodynamics during extubation compared with the use of DES anesthesia in lengthy lumbar spine surgery.

Keywords: DES = desflurane; LOS = length of stay; MBP = mean blood pressure; PACU = postanesthesia care unit; TCI = target-controlled infusion; TIVA; TIVA = total intravenous anesthesia; desflurane; extubation; lengthy spine surgery; lumbar; propofol.