The spectrum of primary immunodeficiency disorders (PIDs) is expanding. It includes typical disorders that primarily present with defective immunity as well as disorders that predominantly involve other systems and show few features of impaired immunity. The rapidly growing list of new immunodeficiency disorders and treatment modalities makes it imperative for providers to stay abreast of the latest and best management strategies. This article presents a brief overview of recent clinical advances in PIDs.
Keywords: Antibody deficiency; Autoimmunity; Immune defect; Immune dysregulation; Immunodeficiency; Innate immune defect; Lymphoproliferation.
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