Inter-comparison of boron concentration measurements at INFN-University of Pavia (Italy) and CNEA (Argentina)

Appl Radiat Isot. 2015 Nov:105:35-39. doi: 10.1016/j.apradiso.2015.07.022. Epub 2015 Jul 23.

Abstract

An inter-comparison of three boron determination techniques was carried out between laboratories from INFN-University of Pavia (Italy) and CNEA (Argentina): alpha spectrometry (alpha-spect), neutron capture radiography (NCR) and quantitative autoradiography (QTA). Samples of different nature were analysed: liquid standards, liver homogenates and tissue samples from different treatment protocols. The techniques showed a good agreement in a concentration range of interest in BNCT (1-100ppm), thus demonstrating their applicability as precise methods to quantify boron and determine its distribution in tissues.

Keywords: Alpha spectrometry; BNCT; Boron imaging; Boron measurements; Inter-comparison; Neutron autoradiography.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Argentina
  • Autoradiography
  • Boron / analysis*
  • Boron Neutron Capture Therapy / standards*
  • Humans
  • Isotopes / analysis
  • Italy
  • Laboratories / standards
  • Liver / chemistry
  • Neutrons
  • Radiography
  • Spectrum Analysis
  • Tissue Distribution

Substances

  • Isotopes
  • Boron