Bioactive C₁₇-Polyacetylenes in Carrots (Daucus carota L.): Current Knowledge and Future Perspectives

J Agric Food Chem. 2015 Oct 28;63(42):9211-22. doi: 10.1021/acs.jafc.5b04357. Epub 2015 Oct 20.

Abstract

C17-polyacetylenes (PAs) are a prominent group of oxylipins and are primarily produced by plants of the families Apiaceae, Araliaceae, and Asteraceae, respectively. Recent studies on the biological activity of polyacetylenes have indicated their potential to improve human health due to anticancer, antifungal, antibacterial, anti-inflammatory, and serotogenic effects. These findings suggest targeting vegetables with elevated levels of bisacetylenic oxylipins, such as falcarinol, by breeding studies. Due to the abundant availability, high diversity of cultivars, worldwide experience, and high agricultural yields, in particular, carrot (Daucus carota L.) genotypes are a very promising target vegetable. This paper provides a review on falcarinol-type C17-polyacetylenes in carrots and a perspective on their potential as a future contributor to improving human health and well-being.

Keywords: Daucus carota L.; bioactive polyacetylenes; bitterness; carrot; falcarindiol; falcarinol; human health.

Publication types

  • Review

MeSH terms

  • Animals
  • Daucus carota / chemistry*
  • Humans
  • Plant Extracts / chemistry*
  • Plant Extracts / pharmacology*
  • Plant Roots / chemistry
  • Polyynes / chemistry*
  • Polyynes / pharmacology*
  • Vegetables / chemistry

Substances

  • Plant Extracts
  • Polyynes