Gallic Acid: Review of the Methods of Determination and Quantification

Crit Rev Anal Chem. 2016 May 3;46(3):257-65. doi: 10.1080/10408347.2015.1095064.

Abstract

Gallic acid (3,4,5 trihydroxybenzoic acid) is a secondary metabolite present in most plants. This metabolite is known to exhibit a range of bioactivities including antioxidant, antimicrobial, anti-inflammatory, and anticancer. There are various methods to analyze gallic acid including spectrometry, chromatography, and capillary electrophoresis, among others. They have been developed to identify and quantify this active ingredient in most biological matrices. The aim of this article is to review the available information on analytical methods for gallic acid, as well as presenting the advantages and limitations of each technique.

Keywords: Analytical methods; gallic acid; polyphenol.

Publication types

  • Review

MeSH terms

  • Chromatography
  • Electrophoresis, Capillary
  • Gallic Acid / analysis*
  • Gallic Acid / metabolism
  • Luminescent Measurements
  • Molecular Structure
  • Spectrum Analysis

Substances

  • Gallic Acid