Abstract
Organo-modified mesoporous silica nanoparticles, loaded with ibuprofen into the pores and functionalized on the external surface with a stable Gd(iii)-DOTA-monoamide chelate, were prepared and explored as potential theranostic probes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Inflammatory Agents, Non-Steroidal / administration & dosage*
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Anti-Inflammatory Agents, Non-Steroidal / chemistry
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
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Chelating Agents / chemistry*
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Heterocyclic Compounds, 1-Ring / chemistry
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Humans
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Ibuprofen / administration & dosage*
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Ibuprofen / chemistry
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Ibuprofen / therapeutic use
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Magnetic Resonance Imaging
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Models, Molecular
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Nanoparticles / chemistry*
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Porosity
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Silicon Dioxide / chemistry*
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Theranostic Nanomedicine*
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Chelating Agents
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Heterocyclic Compounds, 1-Ring
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1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid
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Silicon Dioxide
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Ibuprofen