Pediatric aggressive giant cell granuloma of nasal cavity

Sung Tae Seo; Ki Ryun Kwon; Ki-Sang Rha; Seon-Hwan Kim; Yong Min Kim

doi:10.1016/j.ijscr.2015.09.011

Pediatric aggressive giant cell granuloma of nasal cavity

Int J Surg Case Rep. 2015:16:67-70. doi: 10.1016/j.ijscr.2015.09.011. Epub 2015 Sep 18.

Authors

Sung Tae Seo¹, Ki Ryun Kwon¹, Ki-Sang Rha¹, Seon-Hwan Kim², Yong Min Kim³

Affiliations

¹ Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University School of Medicine, Daejeon, South Korea; Research Institute for Medical Science, Chungnam National University School of Medicine, Daejeon, South Korea.
² Department of Neurosurgery, Chungnam National University School of Medicine, Daejeon, South Korea.
³ Department of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University School of Medicine, Daejeon, South Korea; Research Institute for Medical Science, Chungnam National University School of Medicine, Daejeon, South Korea. Electronic address: entkym@cnu.ac.kr.

Abstract

Introduction: Giant cell granuloma (GCG) is a non-neoplastic osseous proliferative lesion of unknown etiology. Although a benign disease process, GCG can be locally destructive. It is extremely rare to have a pediatric case of GCG occurring in the nasal cavity with intracranial invasion.

Presentation of case: We report a case of an aggressive and recurrent giant cell granuloma with intracranial invasion in a 10 years old female patient which was completely excised with endoscopic craniofacial resection.

Discussion: A literature review on pathogenesis, diagnosis and management is also performed.

Conclusion: The most common treatment for giant cell granuloma is surgery, ranging from simple curettage to resection. However, it must be completely excised in cases of aggressive and extensive lesion because of the high recurrence rate after incomplete removal.

Keywords: Aggressive giant cell granuloma; Endoscopic craniofacial resection.