Mining Genomes of Three Marine Sponge-Associated Actinobacterial Isolates for Secondary Metabolism

Hannes Horn; Ute Hentschel; Usama Ramadan Abdelmohsen

doi:10.1128/genomeA.01106-15

Mining Genomes of Three Marine Sponge-Associated Actinobacterial Isolates for Secondary Metabolism

Genome Announc. 2015 Oct 1;3(5):e01106-15. doi: 10.1128/genomeA.01106-15.

Authors

Hannes Horn¹, Ute Hentschel¹, Usama Ramadan Abdelmohsen²

Affiliations

¹ Department of Botany II, Julius-von-Sachs Institute for Biological Sciences, University of Würzburg, Würzburg, Germany Department of Marine Microbiology, GEOMAR Helmholtz Centre for Ocean Research, RD3 Marine Microbiology and Christian-Albrechts University of Kiel, Kiel, Germany.
² Department of Botany II, Julius-von-Sachs Institute for Biological Sciences, University of Würzburg, Würzburg, Germany usama.ramadan@uni-wuerzburg.de.

Abstract

Here, we report the draft genome sequences of three actinobacterial isolates, Micromonospora sp. RV43, Rubrobacter sp. RV113, and Nocardiopsis sp. RV163 that had previously been isolated from Mediterranean sponges. The draft genomes were analyzed for the presence of gene clusters indicative of secondary metabolism using antiSMASH 3.0 and NapDos pipelines. Our findings demonstrated the chemical richness of sponge-associated actinomycetes and the efficacy of genome mining in exploring the genomic potential of sponge-derived actinomycetes.