Pediatric deceased donor renal transplantation: An approach to decision making I. Pediatric kidney allocation in the USA: The old and the new

Pediatr Transplant. 2015 Nov;19(7):776-84. doi: 10.1111/petr.12569. Epub 2015 Oct 1.

Abstract

Renal transplantation is the treatment of choice for children with end-stage renal disease. More than 50% of children receive a deceased donor renal transplant. Marked disparity between the number of children on the renal transplant wait list and the supply has prompted numerous advances to increase supply as well as maximize the utility of donor organs. Allocation of deceased donor kidneys is based on several criteria. The organ allocation system policy is continually evaluated and changed incrementally to optimize allocation. We, in the United States, are in the process of transitioning into a new kidney allocation system to enhance post-transplant survival benefit, increase utilization of donated kidneys, and increase transplant access for biologically disadvantaged candidates. This review will provide a brief overview of the organ sharing system in the United States, compare the "old" and the "new" allocation system, and discuss the considerations for the pediatric nephrologist while accepting a deceased donor kidney for a particular pediatric patient.

Keywords: allocation; kidney; pediatrics; transplantation.

Publication types

  • Review

MeSH terms

  • Child
  • Clinical Decision-Making / methods*
  • Donor Selection / methods*
  • Donor Selection / organization & administration
  • Health Care Rationing
  • Health Services Accessibility / organization & administration*
  • Humans
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation / methods*
  • Tissue Donors*
  • United States
  • Waiting Lists