Left-colon antegrade enema (LACE): Long-term experience with the Macedo-Malone approach

Neurourol Urodyn. 2017 Jan;36(1):111-115. doi: 10.1002/nau.22880. Epub 2015 Sep 28.

Abstract

Aims: We evaluated the long-term results with a left antegrade continence enema (LACE) approach: "Macedo-Malone (MM) procedure" to define parameters such as clinical durability of the technique and patients' compliance with the method.

Methods: We reviewed the medical records of all patients that underwent the MM procedure in our institution since 2001 and conducted a telephonic interview to investigate the use of the enema and satisfaction with the procedure.

Results: Thirty-five MM procedures were performed, but eight patients lost to follow-up were excluded. Fifteen patients (55%) were female. Myelomeningocele was the clinical diagnoses in 25 (93%). Mean age at surgery was 9 years (3-27 years) and mean follow-up was 75 months (median: 56 months). The indication for LACE was clinically intractable constipation with fecal leakage. Most patients still used the stoma regularly to do the enema (74%). Mean washout time was 27 min (2-90 min). The revision rate due to stenosis was 22.2% (6/27) and all underwent suprafascial revision. We performed one classical MACE by infrafascial approach as a salvage procedure. Overall reoperation rate was 25.8% and fecal continence was 89%. There were no reports of leakage through the stoma. Among patients who still used the stoma, 74% were satisfied with surgery and would strongly recommend the procedure to another patient.

Conclusions: The MM procedure is a straightforward procedure, which can be performed in 15-20 min, avoids additional entero-entero anastomosis, precludes the use of the appendix, and has shown comparable results to either "classical" MACE or other LACE variants. Neurourol. Urodynam. 36:111-115, 2017. © 2015 Wiley Periodicals, Inc.

Keywords: fecal incontinence and constipation; left antegrade continent enema; neurogenic bladder.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Colon*
  • Enema / adverse effects
  • Enema / methods*
  • Fecal Incontinence / etiology
  • Fecal Incontinence / therapy*
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Male
  • Meningomyelocele / complications
  • Meningomyelocele / surgery
  • Patient Compliance
  • Reoperation / statistics & numerical data
  • Retrospective Studies
  • Treatment Outcome
  • Young Adult