Complete genome sequence of Lactobacillus paracasei L9, a new probiotic strain with high lactic acid-producing capacity

Yunyun Jiang; Zhuanyu Li; Fazheng Ren; Songling Liu; Liang Zhao; Erna Sun; Ming Zhang; Huiyuan Guo; Hao Zhang; Lu Jiang; Caiyun Hou

doi:10.1016/j.jbiotec.2015.09.027

Complete genome sequence of Lactobacillus paracasei L9, a new probiotic strain with high lactic acid-producing capacity

J Biotechnol. 2015 Dec 20:216:127-8. doi: 10.1016/j.jbiotec.2015.09.027. Epub 2015 Sep 28.

Authors

Yunyun Jiang¹, Zhuanyu Li², Fazheng Ren³, Songling Liu⁴, Liang Zhao⁴, Erna Sun⁵, Ming Zhang⁶, Huiyuan Guo⁷, Hao Zhang⁶, Lu Jiang⁸, Caiyun Hou⁶

Affiliations

¹ The Research & Innovation Centre of Food Nutrition and Human Health (Beijing), China Agricultural University, Beijing 100083, China; Key Laboratory of Functional Dairy, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083, China.
² The Research & Innovation Centre of Food Nutrition and Human Health (Beijing), China Agricultural University, Beijing 100083, China; Faculty of Food Science and Engineering, Beijing University of Agriculture, Beijing 102206, China.
³ The Research & Innovation Centre of Food Nutrition and Human Health (Beijing), China Agricultural University, Beijing 100083, China; Beijing Higher Institution Engineering Research Center of Animal Product, China Agricultural University, Beijing 10083, China. Electronic address: renfazheng@263.net.
⁴ The Research & Innovation Centre of Food Nutrition and Human Health (Beijing), China Agricultural University, Beijing 100083, China; Beijing Laboratory for Food Quality and Safety, China Agricultural University, Beijing 10083, China.
⁵ Key Laboratory of Functional Dairy, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083, China; Beijing Laboratory for Food Quality and Safety, China Agricultural University, Beijing 10083, China.
⁶ Key Laboratory of Functional Dairy, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083, China.
⁷ The Research & Innovation Centre of Food Nutrition and Human Health (Beijing), China Agricultural University, Beijing 100083, China; Beijing Higher Institution Engineering Research Center of Animal Product, China Agricultural University, Beijing 10083, China.
⁸ Beijing Laboratory for Food Quality and Safety, China Agricultural University, Beijing 10083, China.

PMID: 26415658
DOI: 10.1016/j.jbiotec.2015.09.027

Abstract

Lactobaillus paracasei L9 (CGMCC No. 9800) is a new strain with probiotic properties originating from healthy human intestine. Previous studies evidenced that the strain regulates immune modulation and contributes to the production of high amounts of lactic acid. The genome of L. paracasei L9 contains a circular 3076,437-bp chromosome, encoding 3044 CDSs, 15 rRNA genes and 59 tRNA genes.

Keywords: Genome; LacI; Lactic acid; Lactobaillus paracasei L9.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
Genome, Bacterial*
Lactic Acid / biosynthesis*
Lactobacillus / genetics*
Probiotics / metabolism*

Substances

Lactic Acid