The use of anticoagulants in morbidly obese patients

Cardiol J. 2016;23(1):12-6. doi: 10.5603/CJ.a2015.0054. Epub 2015 Sep 28.

Abstract

Due to its constantly growing incidence, obesity is an increasingly serious social and medical problem. Available data on the use of novel oral anticoagulants in morbidly obese and obese patients are very limited. However, we tried to summarize the available knowledge on the use of anticoagulants in this subpopulation of patients in everyday clinical practice. Studies on the clinical use of anticoagulants provide a poor basis for any adjustment of doses in obese patients as compared to patients with normal body weight. In our opinion, further studies are required in this particular population.

Keywords: anticoagulant drugs; bariatric surgery; factor Xa inhibitors; heparin; morbid obesity; obesity.

Publication types

  • Review

MeSH terms

  • Anticoagulants / administration & dosage*
  • Anticoagulants / adverse effects
  • Anticoagulants / pharmacokinetics
  • Bariatric Surgery
  • Drug Dosage Calculations
  • Humans
  • Obesity, Morbid / complications*
  • Obesity, Morbid / diagnosis
  • Obesity, Morbid / surgery
  • Risk Factors
  • Treatment Outcome

Substances

  • Anticoagulants