Preventing Acute Kidney Injury

Etienne Macedo; Ravindra L Mehta

doi:10.1016/j.ccc.2015.06.011

Preventing Acute Kidney Injury

Crit Care Clin. 2015 Oct;31(4):773-84. doi: 10.1016/j.ccc.2015.06.011. Epub 2015 Jul 29.

Authors

Etienne Macedo¹, Ravindra L Mehta²

Affiliations

¹ Department of Medicine, University of California San Diego, 200 West Arbor Drive, San Diego, CA 92103, USA; Nephrology Division, University of Sao Paulo, Brazil.
² Department of Medicine, University of California San Diego, 200 West Arbor Drive, San Diego, CA 92103, USA. Electronic address: rmehta@ucsd.edu.

PMID: 26410144
DOI: 10.1016/j.ccc.2015.06.011

Abstract

Epidemiologic studies applying the acute kidney injury (AKI) classification system have confirmed the increasing incidence of AKI in different settings and its association with adverse outcomes. AKI is now a recognized important risk factor for new-onset chronic kidney disease, determining acceleration in progression to end-stage renal disease, leading to poor quality of life, disability, and long-term costs. AKI has been associated with high mortalities; however, it is likely that a significant number of deaths associated with AKI could be avoided. This article reviews the key aspects of the 0by25 initiative and its application in critically ill patients.

Keywords: Acute kidney injury; Epidemiology; Prevention.

Publication types

Review

MeSH terms

Acute Kidney Injury / diagnosis
Acute Kidney Injury / epidemiology
Acute Kidney Injury / prevention & control*
Global Health
Health Knowledge, Attitudes, Practice*
Humans
Nephrology* / education
Organizational Objectives
Renal Replacement Therapy
Risk Assessment
Risk Factors
Societies, Medical*