Circulation of a novel human respiratory syncytial virus Group B genotype during the 2014-2015 season in Catalonia (Spain)

Clin Microbiol Infect. 2016 Jan;22(1):97.e5-97.e8. doi: 10.1016/j.cmi.2015.09.013. Epub 2015 Sep 25.

Abstract

Human respiratory syncytial virus (HRSV) is one of the most common viral aetiological agents in the youngest population. In the present study a novel HRSV-B BA genotype is first described based on the phylogenetic analysis of the coding hypervariable region 2 sequences of G protein from strains detected during the 2014-2015 season. Among all strains detected in the last season, 44% belonged to this new genotype. Therefore, it highlights the importance of a continuous HRSV surveillance to monitor the emergence and spread of new genotypes or variants with genetic changes that may affect antigenic and tropism features.

Keywords: Genotypes; molecular epidemiology; respiratory syncytial virus; respiratory infection; surveillance.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genotype*
  • Humans
  • Molecular Epidemiology
  • Phylogeny
  • Respiratory Syncytial Virus Infections / epidemiology*
  • Respiratory Syncytial Virus Infections / virology*
  • Respiratory Syncytial Virus, Human / classification*
  • Respiratory Syncytial Virus, Human / genetics
  • Respiratory Syncytial Virus, Human / isolation & purification*
  • Sequence Analysis, DNA
  • Spain / epidemiology
  • Viral Envelope Proteins / genetics

Substances

  • Viral Envelope Proteins
  • attachment protein G