Helical type coronary bypass graft performance: Experimental investigations

Biomed Mater Eng. 2015:26 Suppl 1:S477-86. doi: 10.3233/BME-151337.

Abstract

Optimal graft design has been an objective of many researchers to find correlations between hemodynamics and graft failure. Compared to planar grafts, the helical graft configurations improve hemodynamic performance including the promotion of flow mixing and reduction of flow stagnation regions. In order to evaluate the advantages and disadvantages of the suggested helical type bypass graft model in comparison to a conventional bypass graft configuration, three experimental models were designed and evaluated. The character of complex vortex structures created in the area between the heel and the occluded section depends on the flow parameters (in the case of the straight graft). We have identified two vortices in the symmetrical plane (proximal and distal to the anastomosis). In the new design of the two-turn helical graft, the stagnation point is eliminated from the anastomoses at different time intervals compared to the conventional straight bypass model The present study indicated that the magnitude of the pressure drop along a helical graft was considerably increased compared to a traditional graft which, while still physiologically advantageous, can be surpassed by an optimal geometry model.

Keywords: Bypass graft; anastomosis; helical graft; hemodynamics; pressure drop.

MeSH terms

  • Blood Flow Velocity
  • Blood Pressure
  • Blood Vessel Prosthesis*
  • Computer Simulation
  • Coronary Artery Bypass / instrumentation*
  • Coronary Artery Bypass / methods*
  • Coronary Circulation
  • Coronary Vessels / physiopathology*
  • Coronary Vessels / surgery*
  • Equipment Failure Analysis
  • Humans
  • Models, Cardiovascular*
  • Prosthesis Design
  • Treatment Outcome