A novel graphene oxide amplified fluorescence anisotropy assay with improved accuracy and sensitivity

Xue Xiao; Yuan Fang Li; Cheng Zhi Huang; Shu Jun Zhen

doi:10.1039/c5cc05902j

A novel graphene oxide amplified fluorescence anisotropy assay with improved accuracy and sensitivity

Chem Commun (Camb). 2015 Nov 18;51(89):16080-3. doi: 10.1039/c5cc05902j.

Authors

Xue Xiao¹, Yuan Fang Li¹, Cheng Zhi Huang², Shu Jun Zhen¹

Affiliations

¹ Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, 400715, Chongqing, P. R. China. zsj@swu.edu.cn.
² Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, 400715, Chongqing, P. R. China. zsj@swu.edu.cn and College of Pharmaceutical Sciences, Southwest University, 400715, Chongqing, P. R. China. chengzhi@swu.edu.cn.

PMID: 26390172
DOI: 10.1039/c5cc05902j

Abstract

In this contribution, a novel and versatile graphene oxide (GO) amplified fluorescence anisotropy (FA) strategy with improved accuracy and sensitivity for the detection of a panel of molecules, single-stranded DNA (ssDNA), adenosine and thrombin, has been successfully developed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biological Assay / methods*
DNA / analysis
Fluorescence Polarization / methods*
Graphite / chemistry*
Limit of Detection
Models, Biological
Oxides / chemistry*

Substances

Oxides
Graphite
DNA