Validity and reliability analysis of the Chinese parent version of the Autism Spectrum Rating Scale (6-18 years)

Hao Zhou; Lili Zhang; Lijie Wu; Xiaobing Zou; Xuerong Luo; Kun Xia; Yimin Wang; Xiu Xu; Xiaoling Ge; Caihong Sun; Hongzhu Deng; Eric Fombonne; Yong-Hui Jiang; Weili Yan; Yi Wang

doi:10.1016/j.psychres.2015.09.003

Validity and reliability analysis of the Chinese parent version of the Autism Spectrum Rating Scale (6-18 years)

Psychiatry Res. 2015 Dec 15;230(2):255-61. doi: 10.1016/j.psychres.2015.09.003. Epub 2015 Sep 8.

Authors

Hao Zhou¹, Lili Zhang¹, Lijie Wu², Xiaobing Zou³, Xuerong Luo⁴, Kun Xia⁵, Yimin Wang¹, Xiu Xu⁶, Xiaoling Ge⁷, Caihong Sun², Hongzhu Deng³, Eric Fombonne⁸, Yong-Hui Jiang⁹, Weili Yan¹⁰, Yi Wang¹¹

Affiliations

¹ No. 399, Wanyuan Road, Minhang District, Division of Neurology, Children's Hospital of Fudan University, Shanghai, China.
² School of Public Health, Harbin Medical University, Harbin, China.
³ Child Development Center, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
⁴ Department of Psychiatry, The Second Xiangya Hospital of Central South University, Changsha, China.
⁵ State Key Laboratory of Medical Genetics, Changsha, China.
⁶ Department of Child Healthcare, Children's Hospital of Fudan University, Shanghai, China.
⁷ Children's Hospital of Fudan University, Shanghai, China.
⁸ Oregon Health & Science University, Portland, OR, USA.
⁹ Division of Medical Genetics, Department of Pediatrics and Neurobiology, Duke University School of Medicine, USA.
¹⁰ Department of Clinical Epidemiology, Children's Hospital of Fudan University, Shanghai, China. Electronic address: yanwl@fudan.edu.cn.
¹¹ No. 399, Wanyuan Road, Minhang District, Division of Neurology, Children's Hospital of Fudan University, Shanghai, China. Electronic address: yiwang@shmu.edu.cn.

PMID: 26384573
DOI: 10.1016/j.psychres.2015.09.003

Abstract

This study aimed to investigate the validity and reliability of the Chinese parent version of the Autism Spectrum Rating Scale (ASRS, 6-18 years) for a general sample of Chinese children. The study involved assessing 1625 community-based subjects aged 6-12 years from four sites (Shanghai, Guangzhou, Changsha, and Harbin city) in China and 211 clinic-based participants aged 6-18 with a confirmed diagnosis of autism spectrum disorders (ASDs). The internal consistency (Cronbach's alpha) ranged from 0.585 to 0.929, and the test-retest reliability (interclass correlations) ranged from 0.542 to 0.749, indicating no significant difference between the two tests at an interval of 2-4 weeks. The construct validity was relatively excellent, and the concurrent validity with the Social Responsiveness Scale (SRS) (Pearson correlations) was 0.732 between the two total scores. Receiver operating characteristics (ROC) analyses showed excellent and comparable discriminant validity of the ASRS with respect to the SRS, with an area under the curve (AUC) of 0.9507 (95% CI: 0.93-0.97) versus 0.9703 (95% CI: 0.96-0.98), respectively. Our data suggested a cutoff ≥60 for the Chinese version of the ASRS, with good accuracy in screening autism symptoms (sensitivity=94.2%, specificity=77%). The Chinese parent version of the ASRS is therefore a reliable and valid tool for screening autistic symptoms in Chinese children in general.

Trial registration: ClinicalTrials.gov NCT02200679.

Keywords: Autism; Child; Epidemiology; Scale; Screening; Validation.

Publication types

Clinical Trial
Multicenter Study
Research Support, Non-U.S. Gov't
Validation Study

MeSH terms

Adolescent
Asian People / psychology*
Autism Spectrum Disorder / diagnosis*
Autism Spectrum Disorder / epidemiology
Autism Spectrum Disorder / psychology*
Child
China / epidemiology
Female
Humans
Male
Parents / psychology*
Psychometrics
Reproducibility of Results
Surveys and Questionnaires / standards*

Associated data

ClinicalTrials.gov/NCT02200679