Detection of Epstein-Barr virus in leucoreduced blood products

Vox Sang. 2016 Feb;110(2):199-201. doi: 10.1111/vox.12330. Epub 2015 Sep 18.

Abstract

This study examined the prevalence of three human herpesviruses (HHV), namely HHV-4 (Epstein-Barr virus/EBV), HHV-6b and HHV-7 in leucoreduced blood products obtained from the Sainte-Justine Hospital blood bank. A total of 100 specimens, including 34 red blood cell concentrates, 33 platelet bags and 33 plasma units, were collected and screened by a sensitive PCR assay using virus-specific primers. Positive units were then retested by quantitative PCR. Of the 100 specimens, one platelet unit tested positive for EBV.

Keywords: herpesviruses; immunosuppression; leucoreduction; transfusion; transplant.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Banks / standards
  • Blood Banks / statistics & numerical data*
  • Blood Cells / virology
  • Herpesvirus 4, Human / isolation & purification*
  • Humans
  • Plasma / virology*