Female pattern hair loss

Curr Probl Dermatol. 2015:47:45-54. doi: 10.1159/000369404. Epub 2015 Feb 20.

Abstract

Female pattern hair loss, or female pattern androgenetic alopecia, is a nonscarring alopecia with a multi-factorial etiology that mostly affects postmenopausal women and is characterized by a reduction in hair density over the crown and frontal scalp. The clinical picture is characterized by a diffuse rarefaction of scalp hair over the mid-frontal scalp and a more-or-less intact frontal hairline without any signs of inflammation or scarring. Although the disease poses only a cosmetic concern, it is chronic and may have a significant negative psychological impact on the affected person. The aim of treating female pattern hair loss is to reduce hair loss and, to a certain extent, succeed in promoting hair regrowth. Various treatment methods are available, but it remains unclear which are the most effective. Early initiation of treatment and the combination of various modalities seem to be more efficacious than monotherapy.

Publication types

  • Review

MeSH terms

  • 5-alpha Reductase Inhibitors / therapeutic use*
  • Administration, Cutaneous
  • Alopecia / diagnosis
  • Alopecia / genetics
  • Alopecia / therapy*
  • Androgen Antagonists / therapeutic use*
  • Androgen Receptor Antagonists / therapeutic use
  • Antifungal Agents / therapeutic use*
  • Cyproterone Acetate / therapeutic use
  • Dutasteride / therapeutic use
  • Female
  • Finasteride / therapeutic use
  • Flutamide / therapeutic use
  • Hair / transplantation*
  • Humans
  • Ketoconazole / therapeutic use*
  • Minoxidil / therapeutic use*
  • Postmenopause
  • Spironolactone / therapeutic use
  • Vasodilator Agents / therapeutic use*

Substances

  • 5-alpha Reductase Inhibitors
  • Androgen Antagonists
  • Androgen Receptor Antagonists
  • Antifungal Agents
  • Vasodilator Agents
  • Spironolactone
  • Cyproterone Acetate
  • Finasteride
  • Minoxidil
  • Flutamide
  • Dutasteride
  • Ketoconazole