Oxidative stress and alopecia areata

J Med Life. 2015;8 Spec Issue(Spec Issue):43-6.

Abstract

Alopecia areata (AA) is an inflammatory and autoimmune disease presenting with non-scarring hair loss. The aethiopathogenesis of alopecia areata is unclear and many factors including autoimmunity, genetic predisposition, emotional and environmental stress are thought to play important roles in its development. Antioxidant/ oxidant balance perturbation is a common feature in autoimmune, emotional and environmental stress. Therefore, our paper discusses the implications of oxidative stress in alopecia areata.

Keywords: alopecia areata; antioxidants; oxidative stress.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alopecia Areata / pathology*
  • Antioxidants / metabolism
  • Enzymes / metabolism
  • Humans
  • Lipid Peroxidation
  • Oxidative Stress*
  • Reactive Oxygen Species / metabolism

Substances

  • Antioxidants
  • Enzymes
  • Reactive Oxygen Species