A Dimensionally Reduced Clustering Methodology for Heterogeneous Occupational Medicine Data Mining

IEEE Trans Nanobioscience. 2015 Oct;14(7):707-15. doi: 10.1109/TNB.2015.2477407. Epub 2015 Sep 9.

Abstract

Clustering is a set of techniques of the statistical learning aimed at finding structures of heterogeneous partitions grouping homogenous data called clusters. There are several fields in which clustering was successfully applied, such as medicine, biology, finance, economics, etc. In this paper, we introduce the notion of clustering in multifactorial data analysis problems. A case study is conducted for an occupational medicine problem with the purpose of analyzing patterns in a population of 813 individuals. To reduce the data set dimensionality, we base our approach on the Principal Component Analysis (PCA), which is the statistical tool most commonly used in factorial analysis. However, the problems in nature, especially in medicine, are often based on heterogeneous-type qualitative-quantitative measurements, whereas PCA only processes quantitative ones. Besides, qualitative data are originally unobservable quantitative responses that are usually binary-coded. Hence, we propose a new set of strategies allowing to simultaneously handle quantitative and qualitative data. The principle of this approach is to perform a projection of the qualitative variables on the subspaces spanned by quantitative ones. Subsequently, an optimal model is allocated to the resulting PCA-regressed subspaces.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cluster Analysis*
  • Computer Simulation
  • Data Mining / methods*
  • Humans
  • Models, Statistical*
  • Occupational Diseases / diagnosis*
  • Occupational Diseases / epidemiology*
  • Occupational Medicine / methods
  • Occupational Medicine / statistics & numerical data*
  • Pattern Recognition, Automated / methods
  • Prevalence
  • Reproducibility of Results
  • Risk Assessment / methods
  • Sensitivity and Specificity