Pulmonary collapse alone provides effective de-airing in cardiac surgery: a prospective randomized study

Perfusion. 2016 May;31(4):320-6. doi: 10.1177/0267659115604712. Epub 2015 Sep 9.

Abstract

Objectives: We previously described and showed that the method for cardiac de-airing involving: (1) bilateral, induced pulmonary collapse by opening both pleurae and disconnecting the ventilator before cardioplegic arrest and (2) gradual pulmonary perfusion and ventilation after cardioplegic arrest is superior to conventional de-airing methods, including carbon dioxide insufflation of the open mediastinum. This study investigated whether one or both components of this method are responsible for the effective de-airing of the heart.

Methods: Twenty patients scheduled for open, left heart surgery were randomized to two de-airing techniques: (1) open pleurae, collapsed lungs and conventional pulmonary perfusion and ventilation; and (2) intact pleurae, expanded lungs and gradual pulmonary perfusion and ventilation.

Results: The number of cerebral microemboli measured by transcranial Doppler sonography was lower in patients with open pleurae 9 (6-36) vs 65 (36-210), p = 0.004. Residual intra-cardiac air grade I or higher as monitored by transesophageal echocardiography 4-6 minutes after weaning from cardiopulmonary bypass was seen in few patients with open pleurae 0 (0%) vs 7 (70%), p = 0.002.

Conclusions: Bilateral, induced pulmonary collapse alone is the key factor for quick and effective de-airing of the heart. Gradual pulmonary perfusion and ventilation, on the other hand, appears to be less important.

Keywords: aortic valve/replacement; cardiopulmonary bypass; surgery/techniques; ultrasound.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cardiac Surgical Procedures / methods*
  • Female
  • Humans
  • Lung* / blood supply
  • Lung* / physiopathology
  • Male
  • Middle Aged
  • Prospective Studies
  • Pulmonary Atelectasis*
  • Respiration, Artificial / methods*
  • Ventilation-Perfusion Ratio*