Co-effects of amines molecules and chitosan films on in vitro calcium carbonate mineralization

Jifei Cui; John F Kennedy; Jun Nie; Guiping Ma

doi:10.1016/j.carbpol.2015.06.096

Co-effects of amines molecules and chitosan films on in vitro calcium carbonate mineralization

Carbohydr Polym. 2015 Nov 20:133:67-73. doi: 10.1016/j.carbpol.2015.06.096. Epub 2015 Jul 11.

Authors

Jifei Cui¹, John F Kennedy², Jun Nie³, Guiping Ma⁴

Affiliations

¹ Beijing Laboratory of Biomedical Materials Beijing University of Chemical Technology, Beijing 100029, PR China.
² Chembiotech Laboratories, University of Birmingham Research Park, Vincent Drive, Birmingham B15 2SQ, UK.
³ Beijing Laboratory of Biomedical Materials Beijing University of Chemical Technology, Beijing 100029, PR China; Chembiotech Laboratories, University of Birmingham Research Park, Vincent Drive, Birmingham B15 2SQ, UK.
⁴ Beijing Laboratory of Biomedical Materials Beijing University of Chemical Technology, Beijing 100029, PR China. Electronic address: magp@mail.buct.edu.cn.

PMID: 26344256
DOI: 10.1016/j.carbpol.2015.06.096

Abstract

Amines monomers, N,N-dimethylaminoethyl methacrylate (DMAEMA), N,N-dimethylethanolamine (DMEA), 2-dimethylaminoethylamine (DMEDA) and N-methiyldiethanolamine (MDEA) were used to induce the formation of calcium carbonate (CaCO3) crystals on chitosan films, by using (NH4)2CO3 diffusion method at ambient temperature. The obtained CaCO3 particles were characterized by scanning electron microscope (SEM), X-ray diffraction (XRD) and Energy dispersive spectroscopy (EDS). The influence of reaction variables, such as the additive concentration and their types were also investigated on the products. The morphologies of CaCO3 crystals, inter-grown in cube-shape, were controlled by DMAEMA and DMEA. It was observed that the morphologies of CaCO3 changed from the cube grown arms to massive calcite with a hole on the face by increasing the concentrations of DMEDA and MDEA. While the precipitation grew on chitosan film without any organic additive, only single cube-shaped crystals were obtained. By these results the possible mechanisms can be proposed that electronic movement of the groups on the monomer effected ions configuration and molecules absorbed on the exposed surface, resulted the change of the surface energy, which caused the change in the morphology of CaCO3.

Keywords: Amine molecules; Calcium carbonate; Chitosan film; Mineralization.

MeSH terms

Amines / chemistry*
Calcium Carbonate / chemical synthesis
Calcium Carbonate / chemistry*
Chitosan / chemistry*

Substances

Amines
Chitosan
Calcium Carbonate