Utilization of organs from donors after circulatory death for vascularized pancreas and islet of Langerhans transplantation: recommendations from an expert group

Transpl Int. 2016 Jul;29(7):798-806. doi: 10.1111/tri.12681. Epub 2015 Sep 24.

Abstract

Donation after circulatory death (DCD) donors are increasingly being used as a source of pancreas allografts for vascularized organ and islet transplantation. We provide practice guidelines aiming to increase DCD pancreas utilization. We review risk assessment and donor selection criteria. We report suggested factors in donor and recipient clinical management and provide an overview of the activities and outcomes of vascularized pancreas and islet transplantation.

Keywords: donation after cardiac death; donation after circulatory death; guidelines; islet of Langerhans; non-heart beating donation; pancreas; review.

Publication types

  • Review

MeSH terms

  • Allografts
  • Brain Death
  • Death*
  • Donor Selection
  • Female
  • Graft Survival
  • Humans
  • Islets of Langerhans / blood supply*
  • Islets of Langerhans Transplantation / methods*
  • Male
  • Middle Aged
  • Organ Preservation
  • Organ Transplantation / methods*
  • Pancreas / blood supply*
  • Postoperative Period
  • Risk Assessment
  • Tissue Donors
  • Tissue and Organ Procurement