[Positioning of headache units in the field of neurology: the importance of OnabotulinumtoxinA and other therapies in the treatment of headaches]

Rev Neurol. 2015:61 Suppl 1:S3-7.
[Article in Spanish]

Abstract

Chronic migraine is a disease that affects 0.5-2.5% of the population, depending on the statistics that are analysed and the definition of chronic migraine that is used. It is extraordinarily disabling, since it does not allow the sufferer to carry out any of their scheduled personal, professional or social activities, and it has a great impact on the patients' quality of life, as measured on disability, quality of life and impact on daily activities scales. Yet, nowadays there are treatments that have proven to be effective in cases of chronic migraine, such as OnabotulinumtoxinA. It is a treatment that is well tolerated and with a high rate of efficacy. Yet it is not only a therapeutic tool, but in the world of headaches it has also opened up the doors to invasive treatments, to the learning of techniques and, in short, to placing headaches in referral units that are usually located in tertiary care hospitals. Furthermore, it has also helped to overcome the idea that patients with headache should be visited exclusively by primary care physicians or general neurologists. This is an opportunity to redefine the field of study and the care for headaches that must be seized. In the future, this is going to be complemented by novel treatments with neurostimulation and probably with monoclonal antibodies against the calcitonin gene-related peptide. A revolution has begun in our knowledge and capacity to act. It is our duty to give it the importance and usage it deserves both for our patients and for us as specialists.

Title: Posicionamiento de las unidades de cefalea en el ambito de la neurologia: la importancia de la OnabotulinumtoxinA y otras terapias en el tratamiento de la cefalea.

La migraña cronica es una enfermedad que afecta al 0,5-2,5% de la poblacion segun las estadisticas que se analicen y la definicion de migraña cronica que se adopte. Es extraordinariamente incapacitante, ya que no permite realizar las actividades personales, profesionales o sociales programadas, y tiene un gran impacto sobre la calidad de vida de los pacientes, medido en escalas de discapacidad, calidad de vida e impacto en la actividad diaria. Sin embargo, actualmente se dispone de tratamientos que han demostrado eficacia en la migraña cronica, como la OnabotulinumtoxinA. Es un tratamiento bien tolerado y con una tasa de eficacia elevada. Pero no es solo una herramienta terapeutica, sino que ha abierto las puertas en el mundo de la cefalea a la realizacion de tratamientos invasivos, al aprendizaje de tecnicas y, en definitiva, a situar la cefalea en unidades de referencia ubicadas, habitualmente, en hospitales de tercer nivel. Ademas, ha ayudado a eliminar el concepto de que los pacientes con cefalea deben ser atendidos exclusivamente por medicos de atencion primaria o neurologos generales. Esta es una oportunidad que debe aprovecharse para redimensionar el campo del estudio y asistencia de la cefalea. En el futuro, esto va a complementarse con novedosos tratamientos con neuroestimulacion y, probablemente, con anticuerpos monoclonales contra el peptido relacionado con el gen de la calcitonina. Se ha iniciado una revolucion en nuestro conocimiento y capacidad de actuacion. Es nuestro deber darle la importancia y uso que se merecen tanto para nuestros pacientes como para nosotros como especialistas.

Publication types

  • Review

MeSH terms

  • Acetylcholine Release Inhibitors / therapeutic use*
  • Antibodies, Monoclonal / therapeutic use
  • Botulinum Toxins, Type A / therapeutic use*
  • Calcitonin / antagonists & inhibitors
  • Cluster Headache / drug therapy
  • Cluster Headache / epidemiology
  • Cluster Headache / prevention & control
  • Cluster Headache / therapy
  • Electric Stimulation Therapy
  • Forecasting
  • Fructose / analogs & derivatives
  • Fructose / therapeutic use
  • Headache Disorders / drug therapy
  • Headache Disorders / epidemiology
  • Headache Disorders / prevention & control
  • Headache Disorders / therapy*
  • Hospital Units* / supply & distribution
  • Humans
  • Migraine Disorders / drug therapy
  • Migraine Disorders / epidemiology
  • Migraine Disorders / prevention & control
  • Migraine Disorders / therapy
  • Nerve Block
  • Neuralgia / drug therapy
  • Neuralgia / epidemiology
  • Neuralgia / prevention & control
  • Neuralgia / therapy
  • Neurology / organization & administration*
  • Prevalence
  • Protein Precursors / antagonists & inhibitors
  • Spain / epidemiology
  • Therapies, Investigational*
  • Topiramate
  • United States / epidemiology

Substances

  • Acetylcholine Release Inhibitors
  • Antibodies, Monoclonal
  • Protein Precursors
  • Topiramate
  • Fructose
  • Calcitonin
  • Botulinum Toxins, Type A