With improvements in cardiac monitoring systems and the effective treatment of arrhythmias, the case-fatality rate of acute myocardial infarction (AMI) has been declining gradually since 1972. But since 1977, despite the great efforts of medical workers in many countries, the lowest case-fatality rate of AMI has still been about 10%. Over many years, our institute has carried out research aimed at improving the treatment of AMI. However, in our institute the case-fatality rate has fluctuated between 15 and 20% in recent years. From March 1986 to January 1987 we adopted a sodium nitroprusside and dopamine intravenous drip in the treatment of 92 cases of AMI and achieved a hospitalization period AMI case-fatality rate of less than 5% (2 patients died). The treatment methods and relevant materials are reported here.