Making Sense of Lymphoma Diagnostics in Small Animal Patients

Clin Lab Med. 2015 Sep;35(3):591-607. doi: 10.1016/j.cll.2015.05.008.

Abstract

This article summarizes and compares the various assays available to aid in the diagnosis and characterization of lymphoma in small animal patients. These techniques include cytology, histopathology, immunocytochemistry and immunohistochemistry, immunophenotyping by flow cytometry, and polymerase chain reaction for clonal antigen receptor gene rearrangement.

Keywords: Cytology; Flow cytometry; Immunohistochemistry/immunocytochemistry; Immunophenotyping; Lymphoma; PCR for clonal antigen receptor gene rearrangement (PARR).

Publication types

  • Review

MeSH terms

  • Animals
  • Biomarkers / blood
  • Cats
  • Cytological Techniques / trends
  • Cytological Techniques / veterinary*
  • Diagnosis, Differential
  • Dogs
  • Early Diagnosis
  • Immunophenotyping / trends
  • Immunophenotyping / veterinary*
  • Lymphoma / blood
  • Lymphoma / diagnosis
  • Lymphoma / pathology
  • Lymphoma / veterinary*
  • Neoplasm Staging / trends
  • Neoplasm Staging / veterinary

Substances

  • Biomarkers