Growth differentiation factor 15 (GDF15) promotes osteoclast differentiation and inhibits osteoblast differentiation and high serum GDF15 levels are associated with multiple myeloma bone disease

Haematologica. 2015 Dec;100(12):e511-4. doi: 10.3324/haematol.2015.124511. Epub 2015 Aug 20.

¹ K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
² Department of Haematology, Rigshospitalet, University of Copenhagen, Denmark.
³ Department of Clinical Biochemistry, Aarhus University Hospital, Denmark.
⁴ Department of Hematology, Skane University Hospital, Malmo, Sweden.
⁵ K.G. Jebsen Center for Myeloma Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway therese.standal@ntnu.no.

No abstract available

Keywords: GDF15; multiple myeloma; osteoblast differentiation; osteoclast differentiation.

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