First case of mesh infection due to Coccidioides spp. and literature review of fungal mesh infections after hernia repair

Mycoses. 2015 Oct;58(10):582-7. doi: 10.1111/myc.12364. Epub 2015 Aug 20.

Abstract

Fungal mesh infections are a rare complication of hernia repairs with mesh. The first case of Coccidioides spp. mesh infection is described, and a systematic literature review of all known fungal mesh infections was performed. Nine cases of fungal mesh infection are reviewed. Female and male patients are equally represented, median age is 49.5 years, and critical illness and preinfection antibiotic use were common. Fungal mesh infections are rare, but potentially fatal, complications of hernias repaired with mesh.

Keywords: Mesh infection; abdominal hernia; coccidioidomycosis; fungal infection.

Publication types

  • Case Reports
  • Review
  • Systematic Review

MeSH terms

  • Adenine / analogs & derivatives
  • Aged
  • Antifungal Agents / therapeutic use
  • Coccidioides / isolation & purification*
  • Coccidioidomycosis / drug therapy
  • Coccidioidomycosis / microbiology*
  • Female
  • Fluconazole / therapeutic use
  • Herniorrhaphy*
  • Humans
  • Hyphae / growth & development
  • Hyphae / ultrastructure
  • Male
  • Middle Aged
  • Piperidines
  • Postoperative Complications / drug therapy
  • Postoperative Complications / microbiology*
  • Pyrazoles / therapeutic use
  • Pyrimidines / therapeutic use
  • Surgical Mesh / microbiology*

Substances

  • Antifungal Agents
  • Piperidines
  • Pyrazoles
  • Pyrimidines
  • ibrutinib
  • Fluconazole
  • Adenine