[The use of psychotropic drugs during breast-feeding]

Pol Merkur Lekarski. 2015 Jul;39(229):47-52.
[Article in Polish]

Abstract

Breast milk is the best source of nutrients and provides much better protection than immune modified milk. In the United States around 500 000 cases of mental disorders affecting pregnant women are diagnosed each year. It is estimated that approximately 1/3 of these women need psychotropic drugs in a period of breast-feeding. Despite the serious consequences of depression and its well-known effect on a newborn, the women are still reluctant to begin pharmacological treatment. The fear of side effects unfortunately still plays an important role in making such a decision. It has been proved that all psychiatric drugs can transfer into breast milk, but their levels are very low or even negligible for the newborn. Most laboratory tests do not reveal an adequate sensitivity to detect these low concentrations. One have to remember that in case of any disturbing symptoms which may result from the use of these drugs, the only procedure is to discontinue breastfeeding immediately. The knowledge of these effects of particular groups of psychotropic drugs in breast-feeding mothers is essential for every practitioner. This knowledge should also be available not only to psychiatrists, but gynecologists and pediatricians as well. For this reason, it seems to be reasonable to summarize the results of previously published studies dealing with the topic.

Keywords: breast-feeding; depression; psychotropic drugs; side effects.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adult
  • Breast Feeding*
  • Depression, Postpartum / drug therapy*
  • Female
  • Humans
  • Infant, Newborn
  • Milk, Human / chemistry*
  • Patient Compliance
  • Psychotropic Drugs / analysis*
  • Psychotropic Drugs / therapeutic use*

Substances

  • Psychotropic Drugs