Spontaneous coronary artery dissection: the management dilemma continues

BMJ Case Rep. 2015 Aug 13:2015:bcr2015211061. doi: 10.1136/bcr-2015-211061.

Abstract

Spontaneous coronary artery dissection (SCAD) is an increasingly recognised cause of acute coronary syndrome, particularly in women. A 36-year-old Caucasian woman presented to our hospital with sudden onset chest pain and was diagnosed with a non-ST elevation myocardial infarction. Coronary angiography revealed mid and distal left anterior descending artery (LAD) dissection with distal LAD occlusion. A short segment of apical LAD filled late with incomplete opacification (Thrombolysis In Myocardial Infarction (TIMI) 1 flow). A decision was made to treat the patient conservatively, with subsequent resolution of dissection over the next 3 months. Our patient made a good clinical recovery with healing of her affected coronary vasculature on subsequent angiogram. The case illustrates that SCAD can be managed conservatively with antiplatelet agents, β-blockers, heparin and statins, if the patient is haemodynamically stable and coronary flow is adequate.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenosine / analogs & derivatives
  • Adenosine / therapeutic use
  • Adult
  • Anticholesteremic Agents / therapeutic use
  • Antihypertensive Agents / therapeutic use
  • Aspirin / therapeutic use
  • Atorvastatin / therapeutic use
  • Carbazoles / therapeutic use
  • Carvedilol
  • Coronary Angiography
  • Coronary Vessel Anomalies / complications
  • Coronary Vessel Anomalies / diagnosis*
  • Coronary Vessel Anomalies / drug therapy*
  • Diagnosis, Differential
  • Echocardiography
  • Electrocardiography
  • Female
  • Humans
  • Myocardial Infarction / complications
  • Myocardial Infarction / drug therapy
  • Myocardial Infarction / etiology
  • Platelet Aggregation Inhibitors / therapeutic use
  • Propanolamines / therapeutic use
  • Purinergic P2Y Receptor Antagonists / therapeutic use
  • Ticagrelor
  • Vascular Diseases / complications
  • Vascular Diseases / congenital*
  • Vascular Diseases / diagnosis
  • Vascular Diseases / drug therapy

Substances

  • Anticholesteremic Agents
  • Antihypertensive Agents
  • Carbazoles
  • Platelet Aggregation Inhibitors
  • Propanolamines
  • Purinergic P2Y Receptor Antagonists
  • Carvedilol
  • Atorvastatin
  • Ticagrelor
  • Adenosine
  • Aspirin

Supplementary concepts

  • Coronary Artery Dissection, Spontaneous