Clopidogrel and CYP2C19: pharmacogenetic testing ready for clinical prime time?

Clin Chem. 2015 Oct;61(10):1235-40. doi: 10.1373/clinchem.2015.238105. Epub 2015 Aug 13.
No abstract available

Publication types

  • Interview
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Clopidogrel
  • Cytochrome P-450 CYP2C19 / genetics*
  • Cytochrome P-450 CYP2C19 / metabolism
  • Drug Monitoring
  • Genotyping Techniques
  • Humans
  • Pharmacogenetics
  • Platelet Aggregation Inhibitors / metabolism
  • Platelet Aggregation Inhibitors / pharmacology
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Polymorphism, Genetic*
  • Prodrugs / metabolism
  • Prodrugs / pharmacology
  • Prodrugs / therapeutic use*
  • Ticlopidine / analogs & derivatives*
  • Ticlopidine / metabolism
  • Ticlopidine / pharmacology
  • Ticlopidine / therapeutic use

Substances

  • Platelet Aggregation Inhibitors
  • Prodrugs
  • Clopidogrel
  • Cytochrome P-450 CYP2C19
  • Ticlopidine