Qing li shan jiu fang (Formulary for Effective Rescuing in the Qingli Reign), compiled by Hanlin Academy of Medical Official in 1048 under the decree of the Emperor, is a medical formulary exclusively used to prevent and control poisonous parasite disease. It is composed of formulae provided by a medical scholar of Fuzhou, Lin Shiyuan, together with other formulae collected by the imperial physicians and so on. Unfortunately, it was lost about after the demise of the Southern Song Dynasty. However, in the Southern Song Dynasty, two books, Liang Kejia's Chun xi san shan zhi and Hong Mai's Yi jian zhi bu, do record the progress of its compilation, parts of its contents and the condition of its spread and application. Moreover, they also describe the kinds, the feature, the epidemic, prevention and cure of parasite poison. It is especially good that this book preserves three famous formulae, including Zhi gu du zheng fang (Orthodox Formula for Treating Parasitic Poisons) (called A Cathartic Formula with 8 Ingredients in the Yuan Dynasty), Jie du wan (Antidote Pills) and He qi tang san (Powder of Decoction for Harmonious Qi), which are of medical significance for the understanding of the property of Qing li shan jiu fang. The Song emperors, the central government and local officials all paid high attention to the spread and application of this book. They not only enacted it to the counties, and provinces, but also carved it on stone steles for popularizing the knowledge of preventing parasitic poisons to medical workers and common people.