Trithorax group genes in hematopoiesis

Oncotarget. 2015 Jul 20;6(20):17855-6. doi: 10.18632/oncotarget.4882.

Authors

Jennifer Chase^{1

2}, Jolanta Grembecka³, Ivan Maillard^{1

4

5}

Affiliations

¹ Center for Stem Cell Biology, Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
² Graduate Program in Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI, USA.
³ Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
⁴ Division of Hematology-Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
⁵ Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.

No abstract available

Publication types

Editorial

MeSH terms

Animals
Antineoplastic Agents / therapeutic use
DNA-Binding Proteins / genetics
DNA-Binding Proteins / metabolism*
Gene Expression Regulation, Leukemic
Hematopoiesis* / genetics
Hematopoietic Stem Cells / metabolism*
Hematopoietic Stem Cells / pathology
Histone-Lysine N-Methyltransferase / genetics
Histone-Lysine N-Methyltransferase / metabolism*
Humans
Leukemia / drug therapy
Leukemia / genetics
Leukemia / metabolism*
Molecular Targeted Therapy
Myeloid-Lymphoid Leukemia Protein / genetics
Myeloid-Lymphoid Leukemia Protein / metabolism*
Neoplastic Stem Cells / drug effects
Neoplastic Stem Cells / metabolism*
Neoplastic Stem Cells / pathology
Signal Transduction
Transcription Factors / genetics
Transcription Factors / metabolism*

Substances

Antineoplastic Agents
DNA-Binding Proteins
KMT2A protein, human
Transcription Factors
Myeloid-Lymphoid Leukemia Protein
ASH1L protein, human
Histone-Lysine N-Methyltransferase

Grants and funding