How is the Xpert MRSA Gen 3 assay (Cepheid) performing on pooled eSwab medium?

Stijn Jonckheere; Kristien Van Vaerenbergh; An Boel; Anne Vankeerberghen; Hans De Beenhouwer

doi:10.1016/j.diagmicrobio.2015.07.006

How is the Xpert MRSA Gen 3 assay (Cepheid) performing on pooled eSwab medium?

Diagn Microbiol Infect Dis. 2015 Nov;83(3):219-21. doi: 10.1016/j.diagmicrobio.2015.07.006. Epub 2015 Jul 14.

Authors

Stijn Jonckheere¹, Kristien Van Vaerenbergh¹, An Boel¹, Anne Vankeerberghen¹, Hans De Beenhouwer²

Affiliations

¹ Clinical Laboratory of Microbiology, OLVZ Aalst, Moorselbaan 164, 9300 Aalst, Belgium.
² Clinical Laboratory of Microbiology, OLVZ Aalst, Moorselbaan 164, 9300 Aalst, Belgium. Electronic address: Hans.De.Beenhouwer@olvz-aalst.be.

PMID: 26256419
DOI: 10.1016/j.diagmicrobio.2015.07.006

Abstract

The performance of the Xpert MRSA Gen 3 was compared to the Xpert MRSA on pooled eSwab media from nose, throat, and perineum using broth enriched cultured as gold standard. A lower specificity was found for the Xpert MRSA Gen 3 compared to the Xpert MRSA (91.8% versus 97.9%; P<0.05).

Keywords: MRSA; Xpert MRSA; Xpert MRSA Gen 3.

Publication types

Evaluation Study

MeSH terms

Humans
Methicillin-Resistant Staphylococcus aureus / isolation & purification*
Molecular Diagnostic Techniques / methods*
Nasal Mucosa / microbiology
Perineum / microbiology
Pharynx / microbiology
Sensitivity and Specificity
Staphylococcal Infections / diagnosis*