Application of MR virtual endoscopy in children with hydrocephalus

Cailei Zhao; Jian Yang; Yungen Gan; Jiangang Liu; Zhen Tan; Guohua Liang; Xianlei Meng; Longwei Sun; Weiguo Cao

doi:10.1016/j.mri.2015.07.013

Application of MR virtual endoscopy in children with hydrocephalus

Magn Reson Imaging. 2015 Dec;33(10):1205-1211. doi: 10.1016/j.mri.2015.07.013. Epub 2015 Aug 4.

Authors

Cailei Zhao¹, Jian Yang², Yungen Gan³, Jiangang Liu⁴, Zhen Tan⁴, Guohua Liang³, Xianlei Meng³, Longwei Sun³, Weiguo Cao³

Affiliations

¹ Department of Radiology, The first affiliated hospital of Xi'an jiaotong university, No. 277, Yantaxi Road, Xi'an, 710061, China; Department of Radiology, Shenzhen children's Hospital, No. 7019, Yitian Road, Shenzhen, 518038, China; The Key Laboratory of Biomedical Information Engineering, Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, P.R. China.
² Department of Radiology, The first affiliated hospital of Xi'an jiaotong university, No. 277, Yantaxi Road, Xi'an, 710061, China; Department of Radiology, Shenzhen children's Hospital, No. 7019, Yitian Road, Shenzhen, 518038, China. Electronic address: yangjian1118@yeah.net.
³ Department of Radiology, The first affiliated hospital of Xi'an jiaotong university, No. 277, Yantaxi Road, Xi'an, 710061, China; Department of Radiology, Shenzhen children's Hospital, No. 7019, Yitian Road, Shenzhen, 518038, China.
⁴ Department of Radiology, The first affiliated hospital of Xi'an jiaotong university, No. 277, Yantaxi Road, Xi'an, 710061, China; Department of Neurosurgery, Shenzhen children's Hospital, No. 7019, Yitian Road, Shenzhen, 518038, China.

PMID: 26248269
DOI: 10.1016/j.mri.2015.07.013

Abstract

Purpose: To evaluate the performance of MR virtual endoscopy (MRVE) in children with hydrocephalus.

Materials and methods: Clinical and imaging data were collected from 15 pediatric patients with hydrocephalus and 15 normal control children. All hydrocephalus patients were confirmed by ventriculoscopy or CT imaging. The cranial 3D-T1 weighted imaging data from fast spoiled gradient echo scan (FSPGR) were transported to working station. VE images of cerebral ventricular cavity were constructed with Navigator software.

Results: Cerebral ventricular MRVE can achieve similar results as ventriculoscopy in demonstrating the morphology of ventricular wall or intracavity lesion. In addition, MRVE can observe the lesion from distal end of obstruction, as well as other areas that are inaccessible to ventriculoscopy. MRVE can also reveal the pathological change of ventricular inner wall surface, and help determine patency of the cerebral aqueduct and fourth ventricle outlet.

Conclusion: MR virtual endoscopy provides a non-invasive diagnostic modality that can be used as a supplemental approach to ventriculoscopy. However, its sensitivity and specificity need to be determined in the large study.

Keywords: Application; Approach; Children; Hydrocephalus; MR; Virtual endoscopy.

MeSH terms

Cerebral Ventricles / pathology*
Endoscopy / methods*
Female
Humans
Hydrocephalus / pathology*
Image Processing, Computer-Assisted / methods*
Imaging, Three-Dimensional / methods
Infant
Magnetic Resonance Imaging / methods*
Male
Sensitivity and Specificity
Software