Suzuki-Miyaura Coupling Reactions of Conjunctive Reagents: 2-Borylated Allylic Sulfones

J Org Chem. 2015 Aug 21;80(16):8168-74. doi: 10.1021/acs.joc.5b01253. Epub 2015 Aug 7.

Abstract

In support of various efforts in our group, we developed methods for the convenient Suzuki-Miyaura coupling of borylated allylic sulfones with various electrophiles in both inter- and the less common intramolecular modes. The procedure facilitates the preparation of a wide variety of sulfones in a straightforward fashion, including six- through eight-membered rings.