A 2-D guinea pig lung proteome map

Simone Schuller; Kjell Sergeant; Jenny Renaut; John J Callanan; Caitriona Scaife; Jarlath E Nally

doi:10.1016/j.dib.2015.04.009

A 2-D guinea pig lung proteome map

Data Brief. 2015 May 27:4:140-5. doi: 10.1016/j.dib.2015.04.009. eCollection 2015 Sep.

Authors

Simone Schuller¹, Kjell Sergeant², Jenny Renaut², John J Callanan³, Caitriona Scaife⁴, Jarlath E Nally⁵

Affiliations

¹ University College Dublin, School of Veterinary Medicine, Belfield, Dublin 4, Ireland ; Vetsuisse Faculty University of Bern, Länggassstrasse 128, 3012 Bern, Switzerland.
² Luxembourg Institute of Science and Technology, Environmental Research and Innovation (ERIN) Department, 4422 Belvaux, Luxembourg.
³ University College Dublin, School of Veterinary Medicine, Belfield, Dublin 4, Ireland ; Conway Institute for Biomolecular & Biomedical Research, Belfield, Dublin 4, Ireland ; Ross University School of Veterinary Medicine, St. Kitts and Nevis, West Indies.
⁴ Conway Institute for Biomolecular & Biomedical Research, Belfield, Dublin 4, Ireland.
⁵ University College Dublin, School of Veterinary Medicine, Belfield, Dublin 4, Ireland ; Conway Institute for Biomolecular & Biomedical Research, Belfield, Dublin 4, Ireland ; Bacterial Diseases of Livestock Research Unit, National Animal Disease Center, Agricultural Research Service, Department of Agriculture, Ames, IA, 50010, United States.

Abstract

Guinea pigs represent an important model for a number of infectious and non-infectious pulmonary diseases. The guinea pig genome has recently been sequenced to full coverage, opening up new research avenues using genomics, transcriptomics and proteomics techniques in this species. In order to further annotate the guinea pig genome and to facilitate future pulmonary proteomics in this species we constructed a 2-D guinea pig proteome map including 486 protein identifications and post translational modifications (PTMs). The map has been up-loaded to the UCD 2D-PAGE open access database (http://proteomics-portal.ucd.ie/). Transit peptides, N-terminal acetylations and other PTMs are available via Peptideatlas (ftp://PASS00619:NM455hi@ftp.peptideatlas.org/). This dataset is associated with a research article published in the Journal of Proteomics [1].