IOP telemetry in the nonhuman primate

Exp Eye Res. 2015 Dec:141:91-8. doi: 10.1016/j.exer.2015.07.015. Epub 2015 Jul 26.

Abstract

This review is focused on continuous IOP monitoring using telemetry systems in the nonhuman primate (NHP), presented in the context that IOP fluctuations at various timescales may be involved in glaucoma pathogenesis and progression. We use glaucoma as the primary framework to discuss how the dynamic nature of IOP might change with age, racial heritage, and disease in the context of glaucoma susceptibility and progression. We focus on the limited work that has been published in IOP telemetry in NHPs, as well as the emerging data and approaches. We review the ongoing efforts to measure continuous IOP, and the strengths, weaknesses and general pitfalls of the various approaches.

Keywords: Biomechanics; Glaucoma; IOP; Nonhuman primate; Telemetry.

Publication types

  • Review

MeSH terms

  • Animals
  • Disease Models, Animal
  • Disease Progression
  • Glaucoma / diagnosis*
  • Glaucoma / physiopathology
  • Intraocular Pressure / physiology*
  • Primates
  • Telemetry / methods*
  • Tonometry, Ocular / methods*