Ovarian hilar proliferations resembling Sertoli cell tumours: microscopic neoplasms or non-neoplastic remnants?

Histopathology. 2016 Mar;68(4):596-602. doi: 10.1111/his.12784. Epub 2015 Sep 4.

Abstract

Aims: To describe four cases of incidentally detected microscopic ovarian hilar Sertoli cell proliferation, a phenomenon that, as far as we are aware, has not been previously reported, and to discuss the differential diagnosis of these lesions.

Methods and results: The proliferations occurred in women aged 35-62 years, and were composed of solid and hollow tubules that were morphologically and immunohistochemically in keeping with Sertoli cells. Two cases were bilateral.

Conclusions: We feel that these uncommon proliferations are likely to represent non-neoplastic embryological remnants rather than hilar Sertoli cell tumours.

Keywords: Hilum; Sertoli cell tumour; immunohistochemistry; ovary; sex cord.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Female
  • Humans
  • Incidental Findings
  • Middle Aged
  • Ovarian Diseases / pathology*
  • Ovarian Neoplasms / pathology
  • Sertoli Cell Tumor / pathology*