Spectrum of Eosinophilic End-Organ Manifestations

Abstract

Eosinophil-associated disorders can affect practically all tissues and organs in the body, either individually or in combination. This article provides an overview of end-organ manifestations of eosinophilia and discusses selected organ systems, including the upper and lower respiratory, cardiovascular, gastrointestinal, nervous, dermatologic, and renal systems. Mechanisms by which eosinophilia leads to end-organ damage are also considered.

Keywords: Churg-Strauss syndrome; Eosinophilic esophagitis; Eosinophilic granulomatous vasculitis; Eosinophils immunology; Eosinophils pathology; Humans; Hypereosinophilic syndrome; Pulmonary eosinophilia.