Abstract
We report the chemical composition of a population of Bornean Laurencia nangii Masuda. A new compound, neolaurene (1), along with five known metabolites, neolaurallene (2), 2,10-dibromo-3-chloro-α-chamigrene (3), deoxyprepacifenol (4), cycloelatanene B (5) and intricatetraol (6), were isolated and their chemical structures elucidated based on spectroscopic data. In addition, their cytotoxicity and antibacterial activity were evaluated.
MeSH terms
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Anti-Bacterial Agents / chemistry*
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Anti-Bacterial Agents / isolation & purification
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Anti-Bacterial Agents / pharmacology
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Bacteria / drug effects
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Cell Line
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Cell Survival / drug effects
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Humans
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Laurencia / chemistry*
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Molecular Structure
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Plant Extracts / chemistry*
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Plant Extracts / isolation & purification
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Plant Extracts / pharmacology
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Rhodophyta / chemistry*
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Sesquiterpenes / chemistry*
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Sesquiterpenes / isolation & purification
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Sesquiterpenes / pharmacology
Substances
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Anti-Bacterial Agents
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Plant Extracts
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Sesquiterpenes