Negative-Strand RNA Virus L Proteins: One Machine, Many Activities

Kalyan Das; Eddy Arnold

doi:10.1016/j.cell.2015.06.063

Negative-Strand RNA Virus L Proteins: One Machine, Many Activities

Cell. 2015 Jul 16;162(2):239-241. doi: 10.1016/j.cell.2015.06.063.

Authors

Kalyan Das¹, Eddy Arnold²

Affiliations

¹ Center for Advanced Biotechnology and Medicine, Rutgers University, 679 Hoes Lane, Piscataway, NJ 08854, USA. Electronic address: kalyan@cabm.rutgers.edu.
² Center for Advanced Biotechnology and Medicine, Rutgers University, 679 Hoes Lane, Piscataway, NJ 08854, USA. Electronic address: arnold@cabm.rutgers.edu.

PMID: 26186183
DOI: 10.1016/j.cell.2015.06.063

Abstract

Structures of L proteins from La Crosse orthobunyavirus and vesicular stomatitis virus reveal insights into RNA synthesis and distinctive mRNA capping mechanisms of segmented and non-segmented negative-sense single-strand RNA viruses.

Publication types

Comment

MeSH terms

DNA-Directed RNA Polymerases / chemistry*
DNA-Directed RNA Polymerases / ultrastructure*
Vesicular stomatitis Indiana virus / chemistry*
Viral Proteins / chemistry*
Viral Proteins / ultrastructure*

Substances

Viral Proteins
DNA-Directed RNA Polymerases